Seville is the headline inland trip from Cadiz: Moorish palaces, Europe's largest Gothic cathedral, and bar-lined neighbourhoods that define southern Spain. From the cruise terminals it is roughly 90 minutes each way by road, so treat it as a full-day outing on longer port calls only.
Cruise ships dock at the Cadiz cruise terminal on the city's Atlantic side, with the historic centre a short walk away. Seville lies 120 km inland along the A-4 and AP-4 motorways — typically 85–95 minutes each way depending on traffic and whether you use the toll road. That travel time alone makes Seville unsuitable for half-day port calls.
Once in Seville, most first-time visitors focus on the UNESCO trio in the centre: the Real Alcázar (book timed entry ahead on cruise days), the Cathedral and Giralda tower, and a stroll through the Santa Cruz quarter. Plaza de España in María Luisa Park is another favourite if your schedule allows a wider loop.
Independent travel means a long taxi fare or rental car with a driver; the train from Cadiz to Seville takes around 1 hour 45 minutes each way and does not leave much margin on a typical cruise schedule. A pre-booked shore excursion is the most reliable way to see the highlights and still make your all-aboard time.
Times and costs are indicative and vary with traffic and demand.